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k7m2 cells  (ATCC)


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    Structured Review

    ATCC k7m2 cells
    The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and <t>K7M2)</t> and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.
    K7m2 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 108 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/k7m2+cells/bio_rxiv__64898__2026__05__07__723520-43-0-6?v=ATCC
    Average 95 stars, based on 108 article reviews
    k7m2 cells - by Bioz Stars, 2026-07
    95/100 stars

    Images

    1) Product Images from "Collagen targeting IL-12 combined with Doxorubicin enhances the anti-tumor effect against osteosarcoma"

    Article Title: Collagen targeting IL-12 combined with Doxorubicin enhances the anti-tumor effect against osteosarcoma

    Journal: bioRxiv

    doi: 10.64898/2026.05.07.723520

    The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and K7M2) and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.
    Figure Legend Snippet: The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and K7M2) and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.

    Techniques Used: Expressing, Confocal Microscopy, Saline

    We inoculated mice with 3 × 10 6 BVM03O OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 5), 416.6 pmol of CBD–IL-12 (i.v., n = 5), and 416.6 pmol of CBD–IL-12 + 2 mg/kg of Dox (i.v., n = 5) on day 35. Dox was additionally injected 3 and 6 days post initial treatment. Average tumor growth curve (a), individual tumor curves (b), and survival curves (c) are shown. We inoculated mice with 5 × 10 6 K7M2 OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 4) and 416.6 pmol of CBD-IL-12 + 2 mg/kg of Dox (i.v., n = 3) once the tumor volume reaches 50 mm 3 . Dox was additionally injected on day 3 and day 6. Average tumor curve (d), individual tumor curves (e), and survival curves (f) are shown. The results are expressed as mean ± S.E.M. Log-rank test was used for (c) and (f) in the statistical analysis. *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.
    Figure Legend Snippet: We inoculated mice with 3 × 10 6 BVM03O OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 5), 416.6 pmol of CBD–IL-12 (i.v., n = 5), and 416.6 pmol of CBD–IL-12 + 2 mg/kg of Dox (i.v., n = 5) on day 35. Dox was additionally injected 3 and 6 days post initial treatment. Average tumor growth curve (a), individual tumor curves (b), and survival curves (c) are shown. We inoculated mice with 5 × 10 6 K7M2 OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 4) and 416.6 pmol of CBD-IL-12 + 2 mg/kg of Dox (i.v., n = 3) once the tumor volume reaches 50 mm 3 . Dox was additionally injected on day 3 and day 6. Average tumor curve (d), individual tumor curves (e), and survival curves (f) are shown. The results are expressed as mean ± S.E.M. Log-rank test was used for (c) and (f) in the statistical analysis. *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.

    Techniques Used: Injection, Saline



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    The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and <t>K7M2)</t> and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.
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    The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and <t>K7M2)</t> and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.
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    Image Search Results


    The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and K7M2) and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.

    Journal: bioRxiv

    Article Title: Collagen targeting IL-12 combined with Doxorubicin enhances the anti-tumor effect against osteosarcoma

    doi: 10.64898/2026.05.07.723520

    Figure Lengend Snippet: The box plot of (a) collagen type I and (b) collagen type III expression in OS tissue compared with paired normal bone samples. (c) Collagen type I and III expression in both mouse (BVM03O and K7M2) and human OS. The cryosections were imaged by confocal microscopy. Nucleus and collagen type I or collagen type III were blue and red, respectively. Scale bars, 250 μm. The results are expressed as mean ± S.E.M. Statistical analysis was performed using an unpaired t-test for (a) and (b). *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.

    Article Snippet: K7M2 cells (CRL-2836) were purchased from ATCC.

    Techniques: Expressing, Confocal Microscopy, Saline

    We inoculated mice with 3 × 10 6 BVM03O OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 5), 416.6 pmol of CBD–IL-12 (i.v., n = 5), and 416.6 pmol of CBD–IL-12 + 2 mg/kg of Dox (i.v., n = 5) on day 35. Dox was additionally injected 3 and 6 days post initial treatment. Average tumor growth curve (a), individual tumor curves (b), and survival curves (c) are shown. We inoculated mice with 5 × 10 6 K7M2 OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 4) and 416.6 pmol of CBD-IL-12 + 2 mg/kg of Dox (i.v., n = 3) once the tumor volume reaches 50 mm 3 . Dox was additionally injected on day 3 and day 6. Average tumor curve (d), individual tumor curves (e), and survival curves (f) are shown. The results are expressed as mean ± S.E.M. Log-rank test was used for (c) and (f) in the statistical analysis. *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.

    Journal: bioRxiv

    Article Title: Collagen targeting IL-12 combined with Doxorubicin enhances the anti-tumor effect against osteosarcoma

    doi: 10.64898/2026.05.07.723520

    Figure Lengend Snippet: We inoculated mice with 3 × 10 6 BVM03O OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 5), 416.6 pmol of CBD–IL-12 (i.v., n = 5), and 416.6 pmol of CBD–IL-12 + 2 mg/kg of Dox (i.v., n = 5) on day 35. Dox was additionally injected 3 and 6 days post initial treatment. Average tumor growth curve (a), individual tumor curves (b), and survival curves (c) are shown. We inoculated mice with 5 × 10 6 K7M2 OS cells subcutaneously on the back skin and the mice were treated with PBS (i.v., n = 4) and 416.6 pmol of CBD-IL-12 + 2 mg/kg of Dox (i.v., n = 3) once the tumor volume reaches 50 mm 3 . Dox was additionally injected on day 3 and day 6. Average tumor curve (d), individual tumor curves (e), and survival curves (f) are shown. The results are expressed as mean ± S.E.M. Log-rank test was used for (c) and (f) in the statistical analysis. *P < 0.05, **P < 0.01. N.S., not significant; PBS, phosphate-buffered saline.

    Article Snippet: K7M2 cells (CRL-2836) were purchased from ATCC.

    Techniques: Injection, Saline